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KP1225 MUC5AC - 3/13 1 mg $385

Product Information

Product NameMUC5AC - 3/13
Purity% Peak Area By HPLC ≥ 95%
Molecular Weight 1907.6
Storage-20°C
Sequence
(One-Letter Code)
GT-T*-PSPVPTTST-T*-SAP
Sequence
(Three-Letter Code)
H - Gly - Thr - Thr* - Pro - Ser - Pro - Val - Pro - Thr - Thr - Ser - Thr - Thr* - Ser - Ala - Pro - OH (Thr* labeled with GalNAc)
DescriptionThis glycopeptide is a MUC5AC peptide with two sites (Thr3 and Thr13) labeled with GalNAc, where the asterisk denotes GalNAc-modified residues. Mucin type O-linked glycosylation is initiated by the action of a family of UDP-GalNAc: polypeptide N-acetylgalactosaminyltransferases (ppGaNTase), which catalyze the transfer of GalNAc from the nucleotide sugar UDP-GalNAc to the hydroxyl group of either serine or threonine.
ReferencesTen Hagen, K. et al. J. Biol. Chem. 277, 22616 (2002).
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