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KP1230 Mycobacterium tuberculosis Protein Ag85A 1 mg $116

Product Information

Product NameMycobacterium tuberculosis Protein Ag85A
Purity% Peak Area By HPLC ≥ 95%
Molecular Weight 2191.5
Storage-20°C
Sequence
(One-Letter Code)
LTSELPGWLQANRHVKPTGS
Sequence
(Three-Letter Code)
H - Leu - Thr - Ser - Glu - Leu - Pro - Gly - Trp - Leu - Gln - Ala - Asn - Arg - His - Val - Lys - Pro - Thr - Gly - Ser - OH
DescriptionThis is a T-cell immunodominant CD8 peptide of the Ag85A Mycobacterium tuberculosis protein, MHC class I H-2Ld-restricted epitope. Because parenterally administered Mycobacterium bovis BCG vaccine confers only limited immune protection from pulmonary tuberculosis, intranasal administration of vector expressing AdAg85A represents an effective way to boost immune protection by parenteral BCG vaccination.
ReferencesSantosuosso, M. et al. Infect. Immun. 74, 4634 (2006).
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