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KP1313 p53 (17 - 26), FITC labeled 1 mg $216

Product Information

Product Namep53 (17 - 26), FITC labeled
Purity% Peak Area By HPLC ≥ 95%
Molecular Weight 1753.1
Storage-20°C
Sequence
(One-Letter Code)
FITC-LC-ETFSDLWKLL-NH2
Sequence
(Three-Letter Code)
FITC - LC - Glu - Thr - Phe - Ser - Asp - Leu - Trp - Lys - Leu - Leu - NH2
DescriptionThis is amino acids 17 to 26 fragment of p53, fluorescent labeled through an LC spacer. This peptide is the Mdm-2 binding domain of p53 known also as p53N. This sequence contains all of the residues that come into contact with the binding domain of Mdm-2. The tumor suppressor protein p53 is important in maintaining genome stability and in preventing cancer development, FITC (Abs/Em=493 nm/517 nm)..
ReferencesYu, G. et al. PNAS 103, 1227 (2006), Wang, Y. et al. J. Biol. Chem. 281, 24803 (2006), Kanovsky, M. et al. PNAS 98, 12438 (2001).
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