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Cat. No. Name Size Price Add Cart
KP1341 Pep - 1 - Cysteamine 1 mg $185

Product Information

Product NamePep - 1 - Cysteamine
Molecular Weight 2950.3
Storage-20°C
Sequence
(One-Letter Code)		Ac-KETWWETWWTEWSQPKKKRKV-cysteamine
Sequence
(Three-Letter Code)		Ac - Lys - Glu - Thr - Trp - Trp - Glu - Thr - Trp - Trp - Thr - Glu - Trp - Ser - Gln - Pro - Lys - Lys - Lys - Arg - Lys - Val - cysteamine
DescriptionPep-1 is one of the synthetic cell-penetrating peptides (CPPs), which has been successfully used to deliver a variety of proteins and other biopharmaceutical macromolecules into cells in a non-disruptive way. It is a CPP with primary amphipathicity (i.e amphipathicity resulting from the amino acid sequence itself, not from the folding structure) that comprises a tryptophan-rich so-called 'hydrophobic' domain, a hydrophilic domain derived from an NLS (nuclear localization signal) of SV40 (simian virus 40) large T-antigen, and a spacer between them. A cysteamine group is present at the C-terminus. The presence of cysteamine group in C terminal seems to play a crucial role in the delivery efficiency of cargoes into cells.
ReferencesHenriques, S. et al. FEBS Letters Vol. 579, 4498 (2005).
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KareBayTM provides scientists and clinicians with a wide range of biotechnological products and science lab supplies for chemical research and analyzing life processes. KareBay's extensive capabilities include commercializing reagents and kits, manufacturing biotech products and providing contract research services to organizations worldwide. Our many global labs, offices, and business partners enable KareBay to extend its products and services to its customer base around the world.

Our products are used for research, laboratory and further evaluation purposes. They are not for human use.
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