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KP1384 Plasmepsin V FRET Substrate 1 mg $185

Product Information

Product NamePlasmepsin V FRET Substrate
Purity% Peak Area By HPLC ≥ 95%
Molecular Weight 1751.1
Storage-20°C
Sequence
(One-Letter Code)
Dabcyl-LNKRLLHETQ-EDANS
Sequence
(Three-Letter Code)
Dabcyl - Leu - Asn - Lys - Arg - Leu - Leu - His - Glu - Thr - Gln - EDANS
DescriptionThis FRET substrate peptide for Plasmepsin V (PMV) is derived from the conserved Plasmodium Export Element (PEXEL) motif of Histidine-Rich Protein II (HRPII). PMV is an ER aspartic protease that recognizes and cleaves the RXL sequence within the PEXEL motif of proteins exported by human malaria parasite Plasmodium falciparum, allowing them to translocate into host erythrocytes.
ReferencesRusso, I. et al. Nature 463, 632 (2010).
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