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KP1393 Poly - γ - D - Glutamic Acid Construct 1 mg $174

Product Information

Product NamePoly - γ - D - Glutamic Acid Construct
Purity% Peak Area By HPLC ≥ 95%
Molecular Weight 2099
Storage-20°C
Sequence
(One-Letter Code)
Ac-(γ-e)15-C-NH2
Sequence
(Three-Letter Code)
Ac - (γ - D - Glu)15 - Cys - NH2
DescriptionThis peptide is a poly-gamma-D-glutamic acid (DPGA)10 construct that relates to the sequence of the Bacillus anthracis capsule which is composed of gamma DPGA. gamma DPGA is an essential virulence factor of B. anthracis. The capsule inhibits innate host defense through its antiphagocytic action. gamma DPGA is a poor immunogen, but when bound to a carrier protein, it elicits serum antibodies.
ReferencesKubler-Kielb, J. et al. Infect. Immun. 74, 4744 (2006).
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