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KP1440 Protease-Activated Receptor-4, PAR-4 Agonist, amide, murine 1 mg $53

Product Information

Product NameProtease-Activated Receptor-4, PAR-4 Agonist, amide, murine
Purity% Peak Area By HPLC ≥ 95%
Molecular Weight 666.8
Storage-20°C
Sequence
(One-Letter Code)
GYPGKF-NH2
Sequence
(Three-Letter Code)
H-Gly-Tyr-Pro-Gly-Lys-Phe-NH2
DescriptionThe family of at least seven transmembrane G protein coupled receptors includes at least four receptor subtypes (PAR1, PAR2, PAR3, PAR4). PAR4 activating peptides, GYPGKF-NH2 and AYPGKG-NH2, produce concentration dependent contractile effects on the muscle.
ReferencesRef: Fang, J. et al. Blood 106, 2671(2005); Mulè,F. et al. Gut. 53, 229 (2004); Sekiguchi, F. et al. Drug Design Rev. 1, 287 (2004); Faruqi, T. et al. J. Biol. Chem. 275, 19728 (2000); Greenberg, D. Biochem. 42, 2702 (2003); Henriksen, R. and V. Hanks, Arterioscler. Thromb. Vasc. Biol. 22, 861 (2002); Gui, Y. et al. Am. J. Physiol. Renal. Physiol. 285, 95 (2003).
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