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Cat. No. Name Size Price Add Cart
KP1441 Protegrine - 1 (PG - 1), amide 1 mg $487

Product Information

Product NameProtegrine - 1 (PG - 1), amide
Purity% Peak Area By HPLC ≥ 95%
Molecular Weight 2155.7
Storage-20°C
Sequence
(One-Letter Code)		RGGRLCYCRRRFCVCVGR-NH2 (disulfide bridge:6-15 and 8-13)
Sequence
(Three-Letter Code)		H - Arg - Gly - Gly - Arg - Leu - Cys - Tyr - Cys - Arg - Arg - Arg - Phe - Cys - Val - Cys - Val - Gly - Arg - NH2 (disulfide bridge:6 - 15 and 8 - 13)
DescriptionThis peptide is Protegrin-1 (PG-1) with a modified C-terminal amide. PG-1 is an 18-amino-acid beta-hairpin antimicrobial peptide found in porcine leukocytes and belongs to the cathelicidin family. PG-1 exhibits broad-spectrum activity unaffected by extracellular NaCl concentrations and is capable of inactivating numerous bacterial strains, Candida albicans, and some enveloped viruses. The efficacy is strongly dependent upon the existence of two disulfide bonds that stabilize the beta-sheet structure.
ReferencesCho, Y. et al. Infect Immun 66, 2486 (1998).
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KareBayTM provides scientists and clinicians with a wide range of biotechnological products and science lab supplies for chemical research and analyzing life processes. KareBay's extensive capabilities include commercializing reagents and kits, manufacturing biotech products and providing contract research services to organizations worldwide. Our many global labs, offices, and business partners enable KareBay to extend its products and services to its customer base around the world.

Our products are used for research, laboratory and further evaluation purposes. They are not for human use.
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