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KP1447 Protein Tyrosine Phosphatase 1B Substrate [ELEF-pY-MDYE-NH2] 1 mg $190

Product Information

Product NameProtein Tyrosine Phosphatase 1B Substrate [ELEF-pY-MDYE-NH2]
Purity% Peak Area By HPLC ≥ 95%
Molecular Weight 1317.4
Storage-20°C
Sequence
(One-Letter Code)
ELEF-pY-MDYE-NH2
Sequence
(Three-Letter Code)
H-Glu-Leu-Glu-Phe-pTyr-Met-Asp-Tyr-Glu-NH2
DescriptionProtein tyrosine phosphorylation is a dynamic reversible process in which the level of phosphorylation, at any time, is the result of phosphatase and/or kinase activity. This balance is critical for control of growth and differentiation. The above substrates can be conveniently used to examine the expression and activity of protein tyrosine phosphatase (e.g. PTP 1B).
ReferencesRef: Dadke, S. and J. Chernoff, Biochem. J. 364, 377 (2002); Dadke, S. et al. Mol. Cell Biochem. 221, 147 (2001). Ukkola, O. and M. Santaniemi, J. Intern. Med. 251, 467 (2002). Vetter, SW. et al. J. Biol. Chem. 275, 2265 (2000).
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