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Cat. No. Name Size Price Add Cart
KP1464 QF - ERP7, FRET 1 mg $173

Product Information

Product NameQF - ERP7, FRET
Purity% Peak Area By HPLC ≥ 95%
Molecular Weight 1132.4
Storage-20°C
Sequence
(One-Letter Code)		Abz-GGFLRRV-EDDnp
Sequence
(Three-Letter Code)		Abz - Gly - Gly - Phe - Leu - Arg - Arg - Val - EDDnp
DescriptionThis FRET peptide, structurally related to enkephalins, proved to be suitable for assaying the endooligopeptidase A activity. Endooligopeptidase A is a putative neuropeptide-metabolizing enzyme. It converts small enkephalin-containing peptides into the corresponding enkephalins and inactivates biopeptides such as bradykinin and neurotensin in vitro. The enzyme only splits the L-R bond, a reaction efficiently blocked by anti-endooligopeptidase A antibodies. Evidence based on the action of inhibitors and on the analysis of QF-ERP7 fragments demonstrated that endooligopeptidase A contributes 100% of the QF-ERP7 cleaving activity found in the cytosol of rabbit brain homogenates.
ReferencesJuliano, L. et al. Biochem. Biophys. Res. Commun. 173, 647 (1990); Ferro, E. et al. J. Cell Biochem. 57, 311 (2004).
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KareBayTM provides scientists and clinicians with a wide range of biotechnological products and science lab supplies for chemical research and analyzing life processes. KareBay's extensive capabilities include commercializing reagents and kits, manufacturing biotech products and providing contract research services to organizations worldwide. Our many global labs, offices, and business partners enable KareBay to extend its products and services to its customer base around the world.

Our products are used for research, laboratory and further evaluation purposes. They are not for human use.
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