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KP1465 R9 - Tat 1 mg $80

Product Information

Product NameR9 - Tat
Purity% Peak Area By HPLC ≥ 95%
Molecular Weight 1803.1
Storage-20°C
Sequence
(One-Letter Code)
GRRRRRRRRRPPQ
Sequence
(Three-Letter Code)
H - Gly - Arg - Arg - Arg - Arg - Arg - Arg - Arg - Arg - Arg - Pro - Pro - Gln - OH
DescriptionThis peptide sequence comprises R9-Tat. R9-Tat is the arginine-substituted analog for the HIV Tat protein (48-60). Similar to Tat (48-60), R9-Tat is internalized by macrophages and translocated to the nucleus and cytoplasm. Additionally, R9-Tat is efficient in intracellular protein delivery, serving as a protein carrier for Carbonic anhydrase into the cell.
ReferencesFutaki, S. et al. Advanced Drug Delivery Reviews 57, 547 (2005).; Futaki, S. et al. J Biol Chem. 276, 5836 (2001).; Futaki, S. et al. J Molec Recognition 16, 260 (2003).
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