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KP1466 Rabies Virus Glycoprotein (RVG) 1 mg $216

Product Information

Product NameRabies Virus Glycoprotein (RVG)
Molecular Weight 3266.7
Storage-20°C
Sequence
(One-Letter Code)
YTIWMPENPRPGTPCDIFTNSRGKRASNG
Sequence
(Three-Letter Code)
H - Tyr - Thr - Ile - Trp - Met - Pro - Glu - Asn - Pro - Arg - Pro - Gly - Thr - Pro - Cys - Asp - Ile - Phe - Thr - Asn - Ser - Arg - Gly - Lys - Arg - Ala - Ser - Asn - Gly - OH
DescriptionThis peptide is a 29 amino acid fragment derived from rabies virus glycoprotein (RVG). Because neurotropic viruses cross the blood-brain barrier to infect brain cells, the same strategy may be used to enter the central nervous system and deliver siRNA to the brain. This peptide specifically binds to the acetylcholine receptor expressed by neuronal cells.
ReferencesKumar, P. et al. Nature 448, 39 (2007).
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