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KP1482 RIAD, FAM labeled 1 mg $243

Product Information

Product NameRIAD, FAM labeled
Purity% Peak Area By HPLC ≥ 95%
Molecular Weight 2653.8
Storage-20°C
Sequence
(One-Letter Code)
LEQYANQLADQIIKEATE-K(FAM)-NH2
Sequence
(Three-Letter Code)
H-Leu-Glu-Gln-Tyr-Ala-Asn-Gln-Leu-Ala-Asp-Gln-Ile-Ile-Lys-Glu-Ala-Thr-Glu-Lys(FAM)-NH2
DescriptionThis cell-soluble high affinity-binding peptide, the RI anchoring disruptor (RIAD) selectively uncouples cAMP-mediated inhibition of T cell function and inhibits progesterone synthesis at the mitochondria in steroid-producing cells. These processes are controlled by the type I PKA holoenzyme and RIAD, and can be used as a tool to define anchored type I PKA signaling events.
ReferencesCarlson, SR. et al. J. Biol. Chem. 281, 21535 (2006).
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