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KP1529 SFLLRNPNDKYEPF, human Thrombin Receptor 42-55 1 mg $74

Product Information

Product NameSFLLRNPNDKYEPF, human Thrombin Receptor 42-55
Purity% Peak Area By HPLC ≥ 95%
Molecular Weight 1739.9
Storage-20°C
Sequence
(One-Letter Code)
SFLLRNPNDKYEPF
Sequence
(Three-Letter Code)
H-Ser-Phe-Leu-Leu-Arg-Asn-Pro-Asn-Asp-Lys-Tyr-Glu-Pro-Phe-OH
DescriptionThis synthetic thrombin receptor agonist peptide corresponds to amino acids 42 to 55 of the human thrombin receptor and fully reproduces the action of thrombin on MMPs in vascular endothelial cells. This peptide (TRP-14) may signal a variety of thrombin′s responses and has been shown to cause platelet aggregation that can evoke a wide range of G-protein dependent responses.
ReferencesRef: Duhamel-Clérin, E. et al. Arterioscler. Thromb. Vasc. Biol. 17, 1931 (1997); Vassallo, R. et al. J. Biol. Chem. 267, 6081 (1992); Y. Sugama and AB. Malik. Circ. Res. 71, 1015 (1992).
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