JAK

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    Cat. No. Name CAS No. Description
    KI0512 AG-490 133550-30-8 AG-490 is a specific janus kinase 2 (JAK2) inhibitor....
    KI4193 AT9283 896466-04-9 ....
    KI0269 AZD1480 935666-88-9 AZD1480 is a potent ATP competitive inhibitor of JAK2 kinase, with an inhibition constant (Ki) of 0.26 nM....
    KI2854 BMS-911543 1271022-90-2 BMS-911543 is a potent JAK2 inhibitor with an IC50 of 1.1 nM....
    KI3853 BRL54443 57477-39-1 ....
    KI0095 CYT387 1056634-68-4 CYT387 is an ATP-competitive inhibitor of JAK1 and JAK2 with IC50 of 11 and 18 nM, respectively....
    KI3900 Ehop-016 1380432-32-5 ....
    KI0207 INCB018424 941678-49-5 INCB018424 is a potent and selective inhibitor of JAK1 (Janus kinase) and JAK2 with IC50 of 3.3 and 2.8 nM, respectively....
    KI0380 LY2784544 1229236-86-5 LY2784544 has been identified as being highly selective for JAK 2-V617F and has advanced into human clinical trials for the treatment of several myeloproliferative disorders....
    KI3702 NVP-BSK805 dihydrochloride 1092499-93-8 NVP-BSK805 can potently suppress JAK2 with IC50 of 0.5 nM, and displays more than 20-fold selectivity towards JAK1, JAK3, and TYK2....
    KI1293 Pacritinib 937272-79-2 Pacritinib is a novel oral JAK2 inhibitor....
    KI1173 TG101209 936091-14-4 TG101209 potently inhibits JAK2, FLT3 and RET kinases with IC50 values of 6, 25 and 17 nM, respectively....
    KI1124 TG101348 936091-26-8 TG101348 is a selective small-molecule inhibitor of JAK2....
    KI0273 Tofacitinib citrate 540737-29-9 Tofacitinib citrate is a PAN-JAK inhibitor with phenomenal selectivity against the human kinome....
    KI3851 WAY100635 maleate 634908-75-1 ....
    KI1071 WP1066 857064-38-1 WP1066 is a novel JAK2 inhibitor....
    KI4238 XL019 945755-56-6 ....

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