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Cat. No. Name Size Price Add Cart
KP1542 SmD1 (83-119) 1 mg $327

Product Information

Product NameSmD1 (83-119)
Purity% Peak Area By HPLC ≥ 95%
Molecular Weight 4011.6
Storage-20°C
Sequence
(One-Letter Code)		VEPKVKSKKREAVAGRGRGRGRGRGRGRGRGRGGPRR
Sequence
(Three-Letter Code)		H - Val - Glu - Pro - Lys - Val - Lys - Ser - Lys - Lys - Arg - Glu - Ala - Val - Ala - Gly - Arg - Gly - Arg - Gly - Arg - Gly - Arg - Gly - Arg - Gly - Arg - Gly - Arg - Gly - Arg - Gly - Arg - Gly - Gly - Pro - Arg - Arg - OH
DescriptionThis is amino acids 83 to 119 fragment of the SmD1 protein (D1 protein of the Sm proteins), one of the small nuclear ribonucleoproteins of the splicing machinery. It is a major target of the B and T cell autoimmune responses associated with human and murine lupus. T cells that recognize this SmD peptide and provide T cell help for both anti-dsDNA and anti-SmD1 (83-119) antibodies were recently identified in lupus-prone NZB/W mice, revealing a new model that may help to explain associations between these autoantibodies.
ReferencesRiemekasten, G. et al. J. Immunol. 173, 5835 (2004).
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KareBayTM provides scientists and clinicians with a wide range of biotechnological products and science lab supplies for chemical research and analyzing life processes. KareBay's extensive capabilities include commercializing reagents and kits, manufacturing biotech products and providing contract research services to organizations worldwide. Our many global labs, offices, and business partners enable KareBay to extend its products and services to its customer base around the world.

Our products are used for research, laboratory and further evaluation purposes. They are not for human use.
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