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KP1562 Substance P (8-11) 1 mg $60

Product Information

Product NameSubstance P (8-11)
Purity% Peak Area By HPLC ≥ 95%
Molecular Weight 465.6
Storage-20°C
Sequence
(One-Letter Code)
FGLM-NH2
Sequence
(Three-Letter Code)
H-Phe-Gly-Leu-Met-NH2
DescriptionSubstance P (SP) is an important neuropeptide that has been implicated in several physiological processes. This SP fragment 8 to 11 amino acids was used in the healing of corneal epithelial wounds study. The combination of FGLM-NH2 and IGF-1 promotes corneal epithelial wound healing in diabetic rats, suggesting that this kind of treatment might prove effective in humans with diabetic keratopathy. Administration of eyedrops containing both FGLM-NH2 and SSSR is effective for the treatment of persistent epithelial defects in individuals with neurotrophic keratopathy.
ReferencesNakamura, M. et al. Diabetologia 46, 839 (2003); Yamada, et al. Invest. Ophthalmol. Vis. Sci. 47, 5018 (2006).
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