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KP1591 TAT-NSF700 Fusion Peptide 1 mg $312

Product Information

Product NameTAT-NSF700 Fusion Peptide
Molecular Weight 4167
Storage-20°C
Sequence
(One-Letter Code)
YGRKKRRQRRR-GGG-LLDYVPIGPRFSNLVLQALLVL
Sequence
(Three-Letter Code)
H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Gly-Gly-Gly-Leu-Leu-Asp-Tyr-Val-Pro-Ile-Gly-Pro-Arg-Phe-Ser-Asn-Leu-Val-Leu-Gln-Ala-Leu-Leu-Val-Leu-OH
DescriptionThis peptide is the N-Ethyl-maleimide-sensitive factor (NSF) inhibitor fusion polypeptide composed of 11-amino acid cell permeable HIV transactivating regulatory protein (TAT) domain fused to a 22 amino acid NSF domain. TAT-NSF700 inhibits thrombin-induced exocytosis of endothelial cells in a dose-responsive manner.
ReferencesMatsushita, K. et al. Mol. Pharmacol. 67,1137 (2005).
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