Home
Services
Organic Synthesis
Peptide Synthesis
Antibody Production
Protein Expression
Bioconjugation Service
Immunoassay Service
Molecular Biology Services
Oligonucleotides Synthesis
RNA Synthesis Service
Polymers & Contract Manufacturing
cGMP Peptide Synthesis Services
cGMP Organic Synthesis Services
Products
Small Molecule Inhibitors and Antagonist
Bioactive Compounds and Agonist
Primary Antibodies
Catalog Peptides
Amino Acids Derivatives
Reagents
Fluorescent dyes
Intermediates
PCR
Proteasomes and Enzymes
Enzyme substrate
Nucleotides
Promotions
Customer Support
About Us
Site Map
Contact Us
Small Molecule Inhibitors and Antagonist
Anti-virus
Cell Cycle
DMPK/Tox
Endocrinology
Epigenetics
GPCR/G-protein
Mitogen-activated Protein Kinases (MAPK)
PI3K/Akt/mTOR
Proteases/Proteasome
Protein Tyrosine Kinases (PTK)
Stem Cells
TGF-Beta/Smad
Transporter
Others
Cat. No. Name Size Price Add Cart
KI0664Albendazole50 mg$154

Chemical Characteristic

Product NameAlbendazole
SynonymsAlbenza, Eskazole, Zentel, Andazol, Alworm
CAS No.54965-21-8
Molecular Weight 265.33
FormulaC12H15N3O2S
Chemical Structure

Biological activities

Albendazole is a benzimidazole drug used for the treatment of a variety of parasitic worm infestations. Albendazole is an effective antimicrosporidial drug. Albendazole exhibits the greatest inhibitory and lethal activity against G. lamblia P1, with an IC50 of 0.01 mg/L and an minimal lethal concentration (MLC) of 34.04 µg/L. [1] Albendazole is a broad spectrum anthelmintic, effective against roundworms, tapeworms, and flukes of domestic animals and humans.18G. lamblia isolates (ACPT 98004, ACPT 98005) are susceptible to albendazole with IC50 ranging from 0.027 to 0.192 µM. [2] The MIC50 of albendazole for E. intestinalis and V. corneae are 8.0 and 55.0 ng/mL. Albendazole is a broadspectrum antiprotozoal benzimidazole which binds to the colchicines binding site of β-tubulin, thereby inhibiting microtubule polymerization. [3] In mice, 2~4 doses of albendazole (> 100 mg/kg twice daily) can complete inhibit cyst excretion and full eliminate trophozoites from the small intestine. [4]

Protocols

Stock solution of albendazole is dissolved in DMSO at a final concentration of 10.0 mg/mL and diluted in tissue culture medium for use. [3]

References

[1] Cedillo-Rivera R, et al. In-vitro susceptibility of Giardia lamblia to albendazole, mebendazole and other chemotherapeutic agents. J Med Microbiol. 1992, 37(3): 221-224. 閵嗏偓閵嗏偓
[2] Cruz A, et al. Isolation, excystation and axenization of Giardia lamblia isolates: in vitro susceptibility to metronidazole and albendazole. J Antimicrob Chemother. 2003, 51(4): 1017-1020. 閵嗏偓閵嗏偓
[3] Didier ES. Effects of albendazole, fumagillin, and TNP-470 on microsporidial replication in vitro. Antimicrob Agents Chemother. 1997, 41(7): 1541-1546. 閵嗏偓閵嗏偓
[4] Reynoldson JA, et al. In vivo efficacy of albendazole against Giardia duodenalis in mice. Parasitol Res. 1991, 77(4): 325-328. 閵嗏偓閵嗏偓

Please click here to fill online order form, and we will make sure to supply you product with detail information. This process usually takes between 24 to 48 hours, depending on products stock avaliability. All inquires and subsequent projects are handled in the strictest confidence and will be backed by a confidentiality agreement if required.
KareBayTM provides scientists and clinicians with a wide range of biotechnological products and science lab supplies for chemical research and analyzing life processes. KareBay's extensive capabilities include commercializing reagents and kits, manufacturing biotech products and providing contract research services to organizations worldwide. Our many global labs, offices, and business partners enable KareBay to extend its products and services to its customer base around the world.

Our products are used for research, laboratory and further evaluation purposes. They are not for human use.
About
KareBayTM Biochem
Sitemap
Blog
Custom Services
Organic Synthesis
Peptide Synthesis
Antibody Production
Protein Expression
Bioconjugation Service
Immunoassry Service
Molecular Biology Services
Oligonucleotides Synthesis
RNA Synthesis Service
cGMP Peptide Synthesis Services
cGMP Organic Synthesis Services
Biochemical Products
Small Molecule Inhibitors
Bioactive Compounds
Primary Antibodies
Peptides
Amino Acids
Reagents
Fluorescent dyes
Intermediates
PCR
Contact Us
KareBayTM Biochem, Inc.
11 Deer Park Drive, Suite 102A
Monmouth Junction, NJ 08852
Telephone
: 732-823-1545

Fax
: 732-823-1349
product@karebaybio.com
service@karebaybio.com
support@karebaybio.com
Follow Us
Follow Karebay on LinkedinFollow IMAGING on Twitter Google+ Facebook