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KI0679AVC1 g$140

Chemical Characteristic

Product NameAVC
Synonymssulfanilamide
CAS No.63-74-1
Molecular Weight 172.2
FormulaC6H8N2O2S
Chemical Structure

Biological activities

Sulfanilamide is a sulfonamide antibacterial. Sulfanilamide inhibits the activity of carbonic anhydrase with an IC50 of 72.2 nM.[1] Sulfanilamide exerts a certain degree of bacteriostatic activity in vitro. Sulfanilamide almost completely inhibits the respiration of P. knowlesi parasites in vitro.[2]

References

[1] Turkmen H, et al. Synthesis of sulfanilamide derivatives and investigation of in vitro inhibitory activities and antimicrobial and physical properties. Bioorg Chem. 2011, 39(3): 114-119. 閵嗏偓閵嗏偓
[2] Coggeshall LT. et al. The selective action of sulfanilamide on the parasites of experimental malaria in monkeys in vivo and in vitro. J Exp Med. 1940, 71(1): 13-20. 閵嗏偓閵嗏偓

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