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KI3750Etofenamate100 mg$270

Chemical Characteristic

Product NameEtofenamate
CAS No.30544-47-9
Molecular Weight 369.34
FormulaC18H18F3NO4
Chemical Name2-(2-Hydroxyethoxy)ethyl 2-[3-(trifluoromethyl)anilino]benzoate
SmilesC(=O)(c1c(cccc1)Nc1cc(ccc1)C(F)(F)F)OCCOCCO
Chemical Structure

Biological activities

Etofenamate is a non-steroidal anti-inflammatory drug used for the treatment joint and muscular pain [1]. It exists as viscous liquid and is used as an analgesic, antirheumatic, antipyretic, and anti-inflammatory. It works by blocking an enzyme in the body known as cyclooxygenase (COX). Etofenamate is marketed in the form of injection and topical gel for the treatment of various conditions like arthritis, muscular rheumatism, muscle pain, periarthritis of the shoulder, joint pain, lower back pain (lumbago), sciatica (ischialgia), sports injuries, and tendonitis. In vivo, it can be used by 3-8 g/day in adults. [2]

References

[1] Chu CY, Chen YL, Lin LJ, et al. Allergic contact dermatitis from etofenamate without cross-sensitization to other anthranilic acid derivatives. Dermatology. 2003,206(4):341-342.
[2] Golcuk Y, Oray D, Atilla OD, et al. Tefennioglu N. Etofenamate associated with Lyell syndrome: a case report. Clin Toxicol (Phila). 2010,48(5):471-472.

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