Cat. No. Name Size Price Add Cart
KI2080LX 16065 mg$390
LX 160610 mg$728
LX 160650 mg$2210
LX 1606100 mg$3640

Chemical Characteristic

Product NameLX 1606
SynonymsLX1606
CAS No.1033805-22-9
Molecular Weight 575
FormulaC27H26ClF3N6O3
Chemical Name(2S)-2-Amino-3-[4-[2-amino-6-[[(1R)-1-[4-chloro-2-(3-methylpyrazol-1-yl)phenyl]-2,2,2-trifluoroethyl]oxy]pyrimidin-4-yl]phenyl]propionic acid ethyl ester
SmilesC(=O)([C@H](Cc1ccc(cc1)c1nc(nc(c1)OC(C(F)(F)F)c1c(cc(cc1)Cl)n1nc(cc1)C)N)N)OCC
Chemical Structure

Biological activities

LX-1606 is a tryptophan hydroxylase (TPH) inhibitor with antiserotonergic activity. Telotristat binds to TPH to block its activity, resulting in a decrease of the production of peripheral serotonin (5-HT) and improving the effects of serotonin-mediated gastrointestinal. It is developed as a potential remedy to overcome the symptoms associated with carcinoid syndrome.[1] And it can be orally delivered.

References

[1] www.wikipedia.org

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