Cat. No. Name Size Price Add Cart
KI3657Oxacillin sodium monohydrate50 mg$156
Oxacillin sodium monohydrate200 mg$272

Chemical Characteristic

Product NameOxacillin sodium monohydrate
CAS No.7240-38-2
Molecular Weight 441.43
FormulaC19H18N3O5S.Na
Chemical Name7-[[3-(2-Chlorophenyl)-5-methyl-oxazol-4-yl]carbonylamino]-3,3-dimethyl-6-oxo-2-thia-5-azabicyclo[3.2.0]heptane-4-carboxylic acid sodium salt monohydrate
Smiles[C@@H]12SC(C(N1C(=O)[C@@H]2NC(=O)c1c(noc1C)c1ccccc1)C(=O)O)(C)C [Na] O
Chemical Structure

Biological activities

Oxacillin sodium (trade name Bactocill) is a narrow-spectrum beta-lactam antibiotic of the penicillin class [1]. Oxacillin is a penicillinase-resistant ?-lactam. It is similar to methicillin, and has replaced methicillin in clinical use. Since it is resistant to penicillinase enzymes, such as that produced by Staphylococcus aureus, it is widely used clinically in the US to treat penicillin-resistant Staphylococcus aureus. In vivo, it can be used by 2-6g/day for adults. [2]

References

[1] Soyege AO, Ajayi AO, Ngwenya E, et al. Vancomycin and oxacillin co-resistance of commensal staphylococci. Jundishapur J Microbiol. 2014, 7(4):e9310.
[2] Pan J, Zhao J, Jiang N. Oral cavity infection: an adverse effect after the treatment of oral cancer in aged individuals. J Appl Oral Sci. 2014, 22(4):261-267.

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