Cat. No. Name Size Price Add Cart
KI2543VUF1046010 mg$439.4
VUF1046050 mg$1755

Chemical Characteristic

Product NameVUF10460
SynonymsN/A
CAS No.1028327-66-3
Molecular Weight 269.34
FormulaC15H19N5
Chemical Name4-(4-Methyl-1-piperazinyl)-6-phenyl-2-Pyrimidinamine
Smilesc1(nc(cc(n1)c1ccccc1)N1CCN(CC1)C)N
Chemical Structure

Biological activities

VUF10460 is a H4 receptor agonist. VUF10460 displays a high affinity for histamine H4 receptor in rat and human with Ki values of 34.7 and 6.0 nM, respectively.[1]

Protocols

In vivo, VUF10460 is dissolved in DMSO.[1]

References

[1] Coruzzi G, et al. Selective histamine H3 and H4 receptor agonists exert opposite effects against the gastric lesions induced by HCl in the rat stomach. Eur J Pharmacol. 2011, 669(1-3): 121-127.

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